diff --git a/cmake/targets/BuildBun.cmake b/cmake/targets/BuildBun.cmake
index c7478dbea2..8acbe2821d 100644
--- a/cmake/targets/BuildBun.cmake
+++ b/cmake/targets/BuildBun.cmake
@@ -1210,6 +1210,29 @@ if(NOT BUN_CPP_ONLY)
     )
   endif()
 
+  # somehow on some Linux systems we need to disable ASLR for ASAN-instrumented binaries to run
+  # when spawned by cmake (they run fine from a shell!)
+  # otherwise they crash with:
+  # ==856230==Shadow memory range interleaves with an existing memory mapping. ASan cannot proceed correctly. ABORTING.
+  # ==856230==ASan shadow was supposed to be located in the [0x00007fff7000-0x10007fff7fff] range.
+  # ==856230==This might be related to ELF_ET_DYN_BASE change in Linux 4.12.
+  # ==856230==See https://github.com/google/sanitizers/issues/856 for possible workarounds.
+  # the linked issue refers to very old kernels but this still happens to us on modern ones.
+  # disabling ASLR to run the binary works around it
+  set(TEST_BUN_COMMAND_BASE
+    env BUN_DEBUG_QUIET_LOGS=1
+    ${BUILD_PATH}/${bunExe} --revision)
+  set(TEST_BUN_COMMAND_ENV_WRAP
+    ${CMAKE_COMMAND} -E env BUN_DEBUG_QUIET_LOGS=1)
+  if (LINUX AND ENABLE_ASAN)
+    set(TEST_BUN_COMMAND
+      ${TEST_BUN_COMMAND_ENV_WRAP} setarch ${CMAKE_HOST_SYSTEM_PROCESSOR} -R ${TEST_BUN_COMMAND_BASE}
+      || ${TEST_BUN_COMMAND_ENV_WRAP} ${TEST_BUN_COMMAND_BASE})
+  else()
+    set(TEST_BUN_COMMAND
+      ${TEST_BUN_COMMAND_ENV_WRAP} ${TEST_BUN_COMMAND_BASE})
+  endif()
+
   register_command(
     TARGET
       ${bun}
@@ -1218,10 +1241,7 @@ if(NOT BUN_CPP_ONLY)
     COMMENT
       "Testing ${bun}"
     COMMAND
-      ${CMAKE_COMMAND}
-      -E env BUN_DEBUG_QUIET_LOGS=1
-      ${BUILD_PATH}/${bunExe}
-        --revision
+      ${TEST_BUN_COMMAND}
     CWD
       ${BUILD_PATH}
   )
diff --git a/patches/tinycc/CMakeLists.txt b/patches/tinycc/CMakeLists.txt
index 971f0952ad..cca27c5c97 100644
--- a/patches/tinycc/CMakeLists.txt
+++ b/patches/tinycc/CMakeLists.txt
@@ -109,11 +109,28 @@ endif()
 add_executable(c2str.exe conftest.c)
 target_compile_options(c2str.exe PRIVATE -DC2STR)
 
+# somehow on some Linux systems we need to disable ASLR for ASAN-instrumented binaries to run
+# when spawned by cmake (they run fine from a shell!)
+# otherwise they crash with:
+# ==856230==Shadow memory range interleaves with an existing memory mapping. ASan cannot proceed correctly. ABORTING.
+# ==856230==ASan shadow was supposed to be located in the [0x00007fff7000-0x10007fff7fff] range.
+# ==856230==This might be related to ELF_ET_DYN_BASE change in Linux 4.12.
+# ==856230==See https://github.com/google/sanitizers/issues/856 for possible workarounds.
+# the linked issue refers to very old kernels but this still happens to us on modern ones.
+# disabling ASLR to run the binary works around it
+set(C2STR_COMMAND $<TARGET_FILE:c2str.exe> include/tccdefs.h tccdefs_.h)
+if(LINUX AND (CMAKE_C_FLAGS MATCHES "-fsanitize"))
+  # our CI builds run in a container where setarch isn't allowed to change the personality.
+  # but the ASan binaries seem to run fine there without ASLR disabled
+  # so, if the command fails with setarch, we try again without (|| ${C2STR_COMMAND}) as a fallback
+  set(C2STR_COMMAND setarch ${CMAKE_HOST_SYSTEM_PROCESSOR} -R ${C2STR_COMMAND} || ${C2STR_COMMAND})
+endif()
+
 add_custom_command(
   TARGET
     c2str.exe POST_BUILD
   COMMAND
-    c2str.exe include/tccdefs.h tccdefs_.h
+    ${C2STR_COMMAND}
   WORKING_DIRECTORY
     ${CMAKE_CURRENT_SOURCE_DIR}
 )